Roger Guedes and Graziano Pelle scored in the first half to seal the win, which helped Shandong build an unassailable lead with 23 points in the Dalian group.
Andreescu, the 2019 US Open champion, missed the opening months of the year because of a knee injury before the pandemic forced the suspension of the sport.
Arrascaeta doubled the visitors lead by holding his ground while under pressure from Damian Diaz and then nonchalantly lofting a shot over Burrai that went in off the underside of the crossbar.
In addition, Mohamed Buya Turay and Brazilian Marcos' goals helped Hebei China Fortune locked up the final seed in Suzhou Division on a 2-0 win over Wuhan Zall. Enditem
The 50-year-old De Boer signed a contract until the 2022 World Cup. He will start his term next month, when the Dutch play Mexico in a friendly, and Bosnia-Herzegovina and Italy in the Nations League.
With one round left, Chongqing has booked a berth in the next stage.
"We played very well against a good team. We won more tackles and played very offensively today," Frankfurt's Sebastian Rode said.
Atletico got a huge boost with Suarez's arrival this week, but the Uruguayan won't be fit to start on Sunday, while Alvaro Morata has now left to join Juventus.
There have been several instances of players challenging a Bundesliga club in such a manner in recent years. Ousmane Dembele and Pierre-Emerick Aubameyang both went on strike to force Borussia Dortmund to allow their transfers to Barcelona and Arsenal respectively.
In the Changzhou division, Kunshan FC edged Changchun Yatai 1-0, Nantong Zhiyun held a 1-1 draw with Sichuan Jiuniu, and Xinjiang Tianshan Leopard tied with Heilongjiang Lava Spring 0-0. Enditem
"This work will continue until the opening of the Olympics," he said. "This crisis requires a lot of flexibilities and sacrifice from all of us.